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Inherited predisposition common in German Shepherd Dog, Collies and English Setters Acquired disease secondary to pancreatitis, or pancreatic duct obstruction May predispose to small intestinal bacterial overgrowth Cause absence of pancreatic exocrine secretion → maldigestionEPI in Dogs Exocrine pancreatic function may be diminished by chronic diseases leading to inadequate production of digestive enzymes and classic signs of maldigestion EPI is a functional diagnosis based on measuring decreased pancreatic secretion capacity by pancreatic function test The exocrine pancreas has a large reserve secretory ca Exocrine pancreatic insufficiency (EPI) is a syndrome that is characterized by decreased production or secretion of digestive enzymes by the pancreas with associated maldigestion EPI causes malassimilation of nutrients (fats, carbs, proteins, vitamins, and trace elements), bacterial proliferation in the small intestine, and morphologic and Signs Treatment Of Exocrine Pancreatic Ins...